SERRI Research Areas are aligned with the US Department of Homeland Security's Science and Technology Integrated Product Teams (IPT). 

Border Security

Border Security includes applied research and technology development to prevent terrorists activities and their weapons from entering the United States and to support CBP officers and agents in enforcing applicable U.S. laws.

Cargo security research includes improved methods for screening and examination by non-intrusive inspection; increased information fusion, anomaly detection, automatic target recognition capability; detection and identification of WMD materials and contraband; capability to screen 100% of cargo; test the feasibility of seal security; detection of intrusion and unauthorized access; test the feasibility of seal security; track domestic high-threat cargo; harden air cargo conveyances and containers; and positive ID of cargo.
Chem/bio defense research includes tools to detect and mitigate animal disease breakouts; policy net assessments to provide fresh perspectives on fundamental elements of the national biodefense strategy; improved tools for integrated CBRN Risk Assessment;  incident characterization capability for response and restoration; improved chembio forensic analysis capability; consequence assessments of attacks on chemical facilities and chem bio attacks on other critical infrastructure; integrated CBRNE sensor reporting capability; handheld rapid biological and chemical detection systems; and detection paradigms and systems for enhanced, emerging and novel biological threats.
Cyber security research includes secure internet protocols including standard security methods; improved capability to model the effects of cyber attacks and understanding of internet topography; comprehensive next-generation network models; composable and scalable secure systems; technologies and standards for managing identities, rights and authorities used in an organization’s networks; information system insider threat detection models and mitigation technologies; analytical techniques for security across the IT system engineering life-cycle; process control systems security. 
Flood Management in the coastal regions of the United States includes research relevant to structural water management and natural disaster recovery.  Structural water management includes an advanced understanding of a range of potential materials and methods to plan, prepare and manage, respond, and recover from a range of natural hazards, especially storm surges and waves from flooding events, under a variety of conditions affecting levees, dams, marshes, spillways and floodgates.  Natural disaster recovery includes such areas as innovative debris removal and disposal, sustainable reconstruction, rapid restoration of services (power, water, transportation, communications, health), and mutual aid.
Research includes science and biometrics-based Research and Development to develop accurate, contactless, near real-time capabilities to improve identification, screening and credentialing of human subjects.
Incident management research includes integrated modeling and simulation capability; personnel monitoring capability; incident management enterprise system; and logistics management tool.
Information sharing research includes data fusion from multiple sensors into common operating picture; improved real-time data sharing of law enforcement information; management of user identities, rights and authorities; distribution of intelligence products; information sharing within/across sectors on terrorists threats; automated, dynamic, real-time data processing and visualization capability; analytic capabilities for structured, unstructured, and streaming data; situational awareness and sensor fusion between law enforcement and intelligence officers.
Infrastructure protection research includes analytical tools to quantify interdependencies and cascading consequences as disruptions occur across critical infrastructure sectors; effective and affordable blast analysis and protection for critical infrastructure; improved understanding of blast failure mechanisms and protection measures for the most vital CI/KR; and advanced, automated and affordable monitoring and surveillance technologies.
Building Regional Resilience includes training and exercise tools for mutual aid structures, continuity of regional operation plans, decision maker awareness and training and business cases for regional resilience.  The potential research for each of these areas might include research in engineering, social political issues, economic issues, training aspects and legal issues.